1EWQ

CRYSTAL STRUCTURE TAQ MUTS COMPLEXED WITH A HETERODUPLEX DNA AT 2.2 A RESOLUTION

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (C)	DNA (5'-D(*GP*CP*GP*AP*CP*GP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*CP*TP*CP*GP*TP*C)-3')	polymer	23	7074.5	1
2	B (D)	DNA (5'-D(*GP*GP*AP*CP*GP*AP*GP*CP*CP*GP*CP*CP*GP*CP*TP*AP*GP*CP*GP*TP*CP*G)-3')	polymer	22	6779.4	1
3	C, D (A, B)	DNA MISMATCH REPAIR PROTEIN MUTS	polymer	765	86386.1	2	UniProt (Q56215) Pfam (PF01624) Pfam (PF05188) Pfam (PF05192) Pfam (PF05190) Pfam (PF00488)	Thermus aquaticus	TAQ MUTS SUBUNIT A
4	E, F, H, I (A, B)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
5	G, J, K, L, M... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	7	Chemie (EDO)
6	P, Q, R, S (C, D, A, B)	water	water		18.0	814	Chemie (HOH)

Sequence modifications

A, B: 1 - 765 (UniProt: Q56215)

PDB	External Database	Details
Mse 1	Met 1	engineered mutation
Mse 4	Met 4	engineered mutation
Mse 70	Met 70	engineered mutation
Mse 88	Met 88	engineered mutation
Mse 201	Met 201	engineered mutation
Mse 250	Met 250	engineered mutation
Mse 481	Met 481	engineered mutation
Mse 574	Met 574	engineered mutation
Mse 586	Met 586	engineered mutation
Mse 640	Met 640	engineered mutation
Mse 643	Met 643	engineered mutation
Mse 744	Met 744	engineered mutation
Mse 762	Met 762	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	186626.1
Non-Polymers*	Number of molecules	11
	Total formula weight	818.7
All*	Total formula weight	187444.9

*Water molecules are not included.