1EFL

HUMAN MALIC ENZYME IN A QUATERNARY COMPLEX WITH NAD, MG, AND TARTRONATE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	MALIC ENZYME	polymer	584	66224.9	4	UniProt (P23368) Pfam (PF00390) Pfam (PF03949) In PDB	Homo sapiens (human)
2	A, B, C, D	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
3	A, B, C, D	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	8	Chemie (NAD)
4	A, B, C, D	TARTRONATE	non-polymer		118.0	4	Chemie (TTN)
5		water	water		18.0	91	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 584 (UniProt: P23368)

PDB	External Database	Details
Mse 29	Met 29	MODIFIED RESIDUE
Mse 38	Met 38	MODIFIED RESIDUE
Mse 47	Met 47	MODIFIED RESIDUE
Mse 75	Met 75	MODIFIED RESIDUE
Mse 86	Met 86	MODIFIED RESIDUE
Mse 108	Met 108	MODIFIED RESIDUE
Mse 177	Met 177	MODIFIED RESIDUE
Mse 219	Met 219	MODIFIED RESIDUE
Mse 239	Met 239	MODIFIED RESIDUE
Mse 325	Met 325	MODIFIED RESIDUE
Mse 327	Met 327	MODIFIED RESIDUE
Mse 343	Met 343	MODIFIED RESIDUE
Mse 407	Met 407	MODIFIED RESIDUE
Mse 539	Met 539	MODIFIED RESIDUE

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	264899.5
Non-Polymers*	Number of molecules	16
	Total formula weight	5876.8
All*	Total formula weight	270776.3

*Water molecules are not included.