1EF3

FIDARESTAT BOUND TO HUMAN ALDOSE REDUCTASE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	ALDOSE REDUCTASE	polymer	315	35767.1	2	UniProt (P15121) Pfam (PF00248) In PDB	Homo sapiens (human)
2	A, B	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	2	Chemie (NAP)
3	A, B	(2S,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE	non-polymer		279.2	2	Chemie (FID)
4		water	water		18.0	25	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71534.3
Non-Polymers*	Number of molecules	4
	Total formula weight	2045.3
All*	Total formula weight	73579.5

*Water molecules are not included.