1EF3
FIDARESTAT BOUND TO HUMAN ALDOSE REDUCTASE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ALDOSE REDUCTASE | polymer | 315 | 35767.1 | 2 | UniProt (P15121) Pfam (PF00248) | Homo sapiens (human) | |
| 2 | C, E (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | D, F (A, B) | (2S,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE | non-polymer | 279.2 | 2 | Chemie (FID) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 25 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71534.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2045.3 | |
| All* | Total formula weight | 73579.5 |
