1EA1

Cytochrome P450 14 alpha-sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with fluconazole

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	CYTOCHROME P450 51-LIKE RV0764C	polymer	455	51499.3	1	UniProt (P77901) Pfam (PF00067) UniProt (by SIFTS) (P9WPP9) In PDB	MYCOBACTERIUM TUBERCULOSIS	CYP51,14ALPHA-STEROL DEMETHYLASE
2	A	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	1	Chemie (HEM)
3	A	2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL	non-polymer		306.3	1	Chemie (TPF)
4		water	water		18.0	175	Chemie (HOH)

Sequence modifications

A: 1 - 451 (UniProt: P77901)
A: 452 - 455 (PDB: 1EA1)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	51499.3
Non-Polymers*	Number of molecules	2
	Total formula weight	922.8
All*	Total formula weight	52422.1

*Water molecules are not included.