1E98
Wild type human thymidylate kinase complexed with AZTMP and ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | THYMIDYLATE KINASE | polymer | 215 | 24222.8 | 1 | UniProt (P23919) Pfam (PF02223) In PDB | HOMO SAPIENS (HUMAN) | DTMP KINASE |
| 2 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 3 | A | 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (ATM) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 172 | Chemie (HOH) |
Sequence modifications
A: 1 - 212 (UniProt: P23919)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Arg 183 | Ser 183 | SEE REMARK 999 |
| Glu 190 | Asp 190 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24222.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 823.0 | |
| All* | Total formula weight | 25045.8 |
