1E7O

A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V44I, V58L MUTATIONS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	SPECTRIN ALPHA CHAIN	polymer	62	7267.3	1	UniProt (P07751) Pfam (PF00018) In PDB	GALLUS GALLUS (CHICKEN)	FODRIN ALPHA CHAIN, SPECTRIN, NON-ERYTHROID ALPHA CHAIN
2	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
3		water	water		18.0	20	Chemie (HOH)

Sequence modifications

A: 1 - 1 (PDB: 1E7O)
A: 2 - 62 (UniProt: P07751)

PDB	External Database	Details
Val 11	Ala 974	engineered mutation
Leu 23	Val 986	engineered mutation
Val 25	Met 988	engineered mutation
Ile 44	Val 1007	engineered mutation
Leu 58	Val 1021	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	7267.3
Non-Polymers*	Number of molecules	1
	Total formula weight	92.1
All*	Total formula weight	7359.4

*Water molecules are not included.