1E2J
The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | THYMIDINE KINASE | polymer | 331 | 35765.1 | 2 | UniProt (P03176) Pfam (PF00693) UniProt (by SIFTS) (P0DTH5) | HERPES SIMPLEX VIRUS (TYPE 1/STRAIN 17) | |
| 2 | C, E (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D, F (A, B) | THYMIDINE | non-polymer | 242.2 | 2 | Chemie (THM) PubChem (44381956) PubChem (46782983) PubChem (3000346) PubChem (57543820) PubChem (57548467) PubChem (58445182) PubChem (59119194) PubChem (5270603) PubChem (68231510) PubChem (68441874) PubChem (68642271) PubChem (68642272) PubChem (1134) PubChem (5789) PubChem (72247) PubChem (159269) PubChem (448456) PubChem (451756) PubChem (453555) PubChem (489518) PubChem (638041) PubChem (121354259) PubChem (7048808) PubChem (142978968) PubChem (144640942) PubChem (163655970) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A, B: 46 - 376 (UniProt: P03176)
| PDB | External Database | Details |
|---|---|---|
| Asn 125 | Gln 125 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71530.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 676.6 | |
| All* | Total formula weight | 72206.7 |
