1E1C

METHYLMALONYL-COA MUTASE H244A Mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	METHYLMALONYL-COA MUTASE ALPHA CHAIN	polymer	727	80070.8	2	UniProt (P11653) Pfam (PF01642) Pfam (PF02310) In PDB	PROPIONIBACTERIUM FREUDENREICHII SUBSP. SHERMANII
2	B, D	METHYLMALONYL-COA MUTASE BETA CHAIN	polymer	637	69430.2	2	UniProt (P11652) Pfam (PF01642) In PDB	PROPIONIBACTERIUM FREUDENREICHII SUBSP. SHERMANII
3	A, C	COBALAMIN	non-polymer		1330.4	2	Chemie (B12)
4	A, C	DESULFO-COENZYME A	non-polymer		735.5	2	Chemie (DCA)
5		water	water		18.0	1525	Chemie (HOH)

Sequence modifications

A, C: 2 - 728 (UniProt: P11653)

PDB	External Database	Details
Ala 244	His 244	engineered mutation

B, D: 1 - 638 (UniProt: P11652)

PDB	External Database	Details
Gly 203	Ala 203	SEE REMARK 999
Glu 330	Asp 330	SEE REMARK 999
Leu 331	Val 331	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	299001.9
Non-Polymers*	Number of molecules	4
	Total formula weight	4131.6
All*	Total formula weight	303133.6

*Water molecules are not included.