1E0A
Cdc42 complexed with the GTPase binding domain of p21 activated kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cell division control protein 42 homolog | polymer | 184 | 20438.6 | 1 | UniProt (P60953) Pfam (PF00071) | Homo sapiens (Human) | G25K GTP-binding protein |
| 2 | B (B) | Serine/threonine-protein kinase PAK 1 | polymer | 46 | 5096.6 | 1 | UniProt (P35465) Pfam (PF00786) | Rattus norvegicus (Rat) | Alpha-PAK,Protein kinase MUK2,p21-activated kinase 1,PAK-1,p68-PAK |
| 3 | C (A) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (A) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A: 1 - 184 (UniProt: P60953)
B: 75 - 118 (UniProt: P35465)
| PDB | External Database | Details |
|---|---|---|
| Leu 61 | Gln 61 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 73 | - | expression tag |
| Ser 74 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25535.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 546.5 | |
| All* | Total formula weight | 26081.7 |
