1DZ5
The NMR structure of the 38KDa U1A protein-PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A | polymer | 101 | 11613.6 | 2 | UniProt (P09012) Pfam (PF00076) | HOMO SAPIENS (HUMAN) | U1 SNRNP A, U1-A, U1A |
| 2 | C, D (C, D) | PIE, RNA (5'-R(*GP*AP*GP*AP*CP*AP*UP*UP*GP*CP*AP*CP*CP* CP*GP*GP*AP*GP*UP*CP*UP*C)-3') | polymer | 22 | 7033.2 | 2 | HOMO SAPIENS |
Sequence modifications
A, B: 1 - 101 (UniProt: P09012)
| PDB | External Database | Details |
|---|---|---|
| His 30 | Tyr 31 | engineered mutation |
| Arg 35 | Gln 36 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 37293.6 | |
| All* | Total formula weight | 37293.6 |
