1DXP
Inhibition of the Hepatitis C Virus NS3/4A Protease. The Crystal Structures of Two Protease-Inhibitor Complexes (apo structure)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | PROTEASE/HELICASE NS3 (P70) | polymer | 187 | 19749.6 | 2 | UniProt (Q81755) Pfam (PF02907) UniProt (by SIFTS) (P26662) In PDB | HEPATITIS C VIRUS (ISOLATE TAIWAN) | |
| 2 | C, D | NONSTRUCTURAL PROTEIN NS4A (P4) | polymer | 16 | 1686.1 | 2 | UniProt (Q81755) UniProt (by SIFTS) (P26662) In PDB | HEPATITIS C VIRUS | |
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 209 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 42871.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 222.9 | |
| All* | Total formula weight | 43094.2 |
