1DWD
CRYSTALLOGRAPHIC ANALYSIS AT 3.0-ANGSTROMS RESOLUTION OF THE BINDING TO HUMAN THROMBIN OF FOUR ACTIVE SITE-DIRECTED INHIBITORS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | ALPHA-THROMBIN (SMALL SUBUNIT) | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | |
| 2 | B (H) | ALPHA-THROMBIN (LARGE SUBUNIT) | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | |
| 3 | C (I) | HIRUDIN IIIA | polymer | 11 | 1411.5 | 1 | UniProt (P28508) UniProt (by SIFTS) (P28504) | Hirudo medicinalis (medicinal leech) | |
| 4 | D (H) | 1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimidoyl-D-phenylalanyl]piperidine | non-polymer | 521.6 | 1 | BIRD (PRD_000451) Chemie (MID) | |||
| 5 | E, F, G (L, H, I) | water | water | 18.0 | 50 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 35288.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 521.6 | |
| All* | Total formula weight | 35809.8 |
