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1DRF

CRYSTAL STRUCTURE OF HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DIHYDROFOLATE REDUCTASEpolymer18621349.51UniProt (P00374)
Pfam (PF00186)
Homo sapiens (human)
2B, C
(A)
SULFATE IONnon-polymer96.12Chemie (SO4)
3D
(A)
FOLIC ACIDnon-polymer441.41Chemie (FOL)
4E
(A)
waterwater18.0249Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight21349.5
Non-Polymers*Number of molecules3
Total formula weight633.5
All*Total formula weight21983.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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