1DIG
HUMAN METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE COMPLEXED WITH NADP AND INHIBITOR LY374571
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE | polymer | 306 | 33338.4 | 2 | UniProt (P11586) Pfam (PF00763) Pfam (PF02882) In PDB | Homo sapiens (human) | DC301 |
| 2 | A, B | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | A | [[N'-(2,5-DIAMINO-6-HYDROXY-PYRIMIDIN-4-YL)-UREAYL]-PHEN-4-YL]-CARBONYL-GLUTAMIC ACID | non-polymer | 433.4 | 1 | Chemie (L37) | |||
| 4 | B | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66676.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1979.2 | |
| All* | Total formula weight | 68656.1 |
