1DIB
HUMAN METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE COMPLEXED WITH NADP AND INHIBITOR LY345899
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLOHYDROLASE | polymer | 306 | 33338.4 | 2 | UniProt (P11586) Pfam (PF00763) Pfam (PF02882) | Homo sapiens (human) | DC301 |
| 2 | C, E (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | D (A) | 4-(7-AMINO-9-HYDROXY-1-OXO-3,3A,4,5-TETRAHYDRO-2,5,6,8,9B-PENTAAZA-CYCLOPENTA[A]NAPHTHALEN-2-YL)-PHENYLCARBONYL-GLUTAMI C ACID | non-polymer | 471.4 | 1 | Chemie (L34) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66676.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1958.2 | |
| All* | Total formula weight | 68635.1 |
