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1DG7

DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND 4-BROMO WR99210

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DIHYDROFOLATE REDUCTASEpolymer15917661.01UniProt (P0A546)
Pfam (PF00186)
UniProt (by SIFTS) (P9WNX1)
Mycobacterium tuberculosisDHFR
2B
(A)
1-[3-(4-BROMO-PHENOXY)-PROPOXY]-6,6-DIMETHYL-1.6-DIHYDRO-[1,3,5]TRIAZINE-2,4-DIAMINEnon-polymer370.21Chemie (WRB)
3C
(A)
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.41Chemie (NDP)
4D, E, F, G
(A)
GLYCEROLnon-polymer92.14Chemie (GOL)
5H
(A)
waterwater18.0175Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight17661.0
Non-Polymers*Number of molecules6
Total formula weight1484.0
All*Total formula weight19145.0
*Water molecules are not included.

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PDB entries from 2025-07-02

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