1D8D
CO-CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A K-RAS4B PEPTIDE SUBSTRATE AND FPP ANALOG AT 2.0A RESOLUTION
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | farnesyltransferase (alpha subunit) | polymer | 377 | 44098.1 | 1 | UniProt (Q04631) Pfam (PF01239) | Rattus norvegicus (Norway rat) | FTASE |
| 2 | B (B) | farnesyltransferase (beta subunit) | polymer | 437 | 48722.3 | 1 | UniProt (Q02293) Pfam (PF00432) | Rattus norvegicus (Norway rat) | FTASE |
| 3 | C (P) | K-RAS4B PEPTIDE SUBSTRATE | polymer | 11 | 1298.7 | 1 | UniProt (P01116) | ||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E, F, H, I (B, P) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 6 | G (B) | [(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID | non-polymer | 359.4 | 1 | Chemie (FII) | |||
| 7 | J, K, L (A, B, P) | water | water | 18.0 | 447 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 94119.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 661.0 | |
| All* | Total formula weight | 94780.1 |
