1D5M
X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH PEPTIDE AND SEB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA CLASS II HISTOCOMPATIBILITY ANTIGEN | polymer | 181 | 21084.8 | 1 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (human) | HLA-DR4 |
| 2 | B (B) | HLA CLASS II HISTOCOMPATIBILITY ANTIGEN | polymer | 192 | 22506.0 | 1 | UniProt (P13760) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) | Homo sapiens (human) | HLA-DR4 |
| 3 | C (C) | ENTEROTOXIN TYPE B | polymer | 239 | 28411.1 | 1 | UniProt (P01552) Pfam (PF01123) Pfam (PF02876) | Staphylococcus aureus | SEB, SUPERANTIGEN |
| 4 | D (D) | INHIBITOR | polymer | 9 | 929.2 | 1 | BIRD (PRD_000233) | synthetic construct | |
| 5 | E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
B: 1 - 192 (UniProt: P13760)
| PDB | External Database | Details |
|---|---|---|
| Val 180 | Leu 209 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 72931.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 73152.3 |
