1D5L

CRYSTAL STRUCTURE OF CYANIDE-BOUND HUMAN MYELOPEROXIDASE ISOFORM C AT PH 5.5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, B)	MYELOPEROXIDASE	polymer	104	11903.3	2	UniProt (P05164)	Homo sapiens (human)
2	B, D (C, D)	MYELOPEROXIDASE	polymer	466	53234.2	2	UniProt (P05164) Pfam (PF03098)	Homo sapiens (human)
3	E, F (E, F)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1057.0	2	In PDB GlyTouCan (G82348BZ)
4	G, T (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5	H, N, Z (A, C, D)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
6	DA, I, S, U (D, A, C, B)	CYANIDE ION	non-polymer		26.0	4	Chemie (CYN)
7	J, V (C, D)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
8	K, L, W, X (C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
9	M, Y (C, D)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
10	AA, BA, CA, O, P... (D, C)	ACETATE ION	non-polymer		59.0	7	Chemie (ACT)
11	EA, FA, GA, HA (A, C, B, D)	water	water		18.0	866	Chemie (HOH)

Sequence modifications

C, D: 113 - 578 (UniProt: P05164)

PDB	External Database	Details
Cso 150	Cys 315	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	130275.1
Branched	Number of molecules	2
	Total formula weight	2113.9
Non-Polymers*	Number of molecules	24
	Total formula weight	3074.4
All*	Total formula weight	135463.4

*Water molecules are not included.