1CMK
CRYSTAL STRUCTURES OF THE MYRISTYLATED CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE REVEAL OPEN AND CLOSED CONFORMATIONS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | E | cAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT | polymer | 350 | 40705.4 | 1 | UniProt (P00517) Pfam (PF00069) UniProt (by SIFTS) (P36887) In PDB | Sus scrofa (pig) | |
| 2 | I | cAMP-dependent protein kinase inhibitor, alpha form | polymer | 22 | 2452.7 | 1 | UniProt (P61925) Pfam (PF02827) In PDB | Homo sapiens | |
| 3 | E | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) | |||
| 4 | I | IODIDE ION | non-polymer | 126.9 | 2 | Chemie (IOD) |
Sequence modifications
E: 1 - 350 (UniProt: P00517)
| PDB | External Database | Details |
|---|---|---|
| Lys 63 | Met 63 | CONFLICT |
| Phe 69 | Tyr 69 | CONFLICT |
| Tyr 108 | Phe 108 | CONFLICT |
| Asp 286 | Asn 286 | CONFLICT |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43158.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 482.2 | |
| All* | Total formula weight | 43640.3 |
