1C88
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN (PROTEIN-TYROSINE PHOSPHATASE 1B) | polymer | 298 | 34720.6 | 1 | UniProt (P18031) Pfam (PF00102) | Homo sapiens (human) | PTP1B |
| 2 | B (A) | 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID | non-polymer | 270.3 | 1 | Chemie (OTA) | |||
| 3 | C (A) | water | water | 18.0 | 225 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Thr 151 | Ser 151 | conflict |
| Asp 252 | Glu 252 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34720.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 270.3 | |
| All* | Total formula weight | 34990.8 |
