1C5W
STRUCTURAL BASIS FOR SELECTIVITY OF A SMALL MOLECULE, S1-BINDING, SUB-MICROMOLAR INHIBITOR OF UROKINASE TYPE PLASMINOGEN ACTIVATOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | PROTEIN (UROKINASE-TYPE PLASMINOGEN ACTIVATOR) | polymer | 23 | 2708.2 | 1 | UniProt (P00749) In PDB | Homo sapiens (human) | |
| 2 | B | PROTEIN (UROKINASE-TYPE PLASMINOGEN ACTIVATOR) | polymer | 253 | 28435.4 | 1 | UniProt (P00749) Pfam (PF00089) In PDB | Homo sapiens (human) | |
| 3 | B | CITRATE ANION | non-polymer | 189.1 | 3 | Chemie (FLC) | |||
| 4 | B | 4-IODOBENZO[B]THIOPHENE-2-CARBOXAMIDINE | non-polymer | 303.1 | 1 | Chemie (ESI) | |||
| 5 | water | water | 18.0 | 294 | Chemie (HOH) |
Sequence modifications
B: 16 - 250 (UniProt: P00749)
| PDB | External Database | Details |
|---|---|---|
| Ala 145 | Asn 322 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31143.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 870.4 | |
| All* | Total formula weight | 32014.1 |
