1C5N
STRUCTURAL BASIS FOR SELECTIVITY OF A SMALL MOLECULE, S1-BINDING, SUB-MICROMOLAR INHIBITOR OF UROKINASE TYPE PLASMINOGEN ACTIVATOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Thrombin light chain | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | |
| 2 | B (H) | Thrombin heavy chain | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | |
| 3 | C (I) | Hirudin | polymer | 10 | 1363.4 | 1 | UniProt (P28504) | Hirudo medicinalis | |
| 4 | D (H) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | E (H) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | F (H) | 4-IODOBENZO[B]THIOPHENE-2-CARBOXAMIDINE | non-polymer | 303.1 | 1 | Chemie (ESI) | |||
| 7 | G, H, I (L, H, I) | water | water | 18.0 | 255 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 35240.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 366.2 | |
| All* | Total formula weight | 35606.4 |
