1BQI
USE OF PAPAIN AS A MODEL FOR THE STRUCTURE-BASED DESIGN OF CATHEPSIN K INHIBITORS. CRYSTAL STRUCTURES OF TWO PAPAIN INHIBITOR COMPLEXES DEMONSTRATE BINDING TO S'-SUBSITES.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PAPAIN | polymer | 212 | 23449.3 | 1 | UniProt (P00784) Pfam (PF00112) | Carica papaya (papaya) | |
| 2 | B (A) | CARBOBENZYLOXY-(L)-LEUCINYL-(L)LEUCINYL METHOXYMETHYLKETONE | non-polymer | 408.5 | 1 | Chemie (SBA) | |||
| 3 | C (A) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
A: 1 - 212 (UniProt: P00784)
| PDB | External Database | Details |
|---|---|---|
| Gln 47 | Glu 180 | conflict |
| Gln 118 | Glu 251 | conflict |
| Gln 135 | Glu 268 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23449.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 408.5 | |
| All* | Total formula weight | 23857.9 |
