1BIZ

HIV-1 INTEGRASE CORE DOMAIN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	HIV-1 INTEGRASE	polymer	166	18178.7	2	UniProt (Q76353) UniProt (by SIFTS) (P12497)	Human immunodeficiency virus 1
2	C, D, E, F (A, B)	CACODYLATE ION	non-polymer		137.0	4	Chemie (CAC)
3	G, H (A, B)	water	water		18.0	212	Chemie (HOH)

Sequence modifications

A, B: 47 - 212 (UniProt: Q76353)

PDB	External Database	Details
Ser 48	Glu 763	conflict
His 49	Ala 764	conflict
Ser 56	Cys 771	engineered mutation
Lys 185	Phe 900	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	36357.4
Non-Polymers*	Number of molecules	4
	Total formula weight	548.0
All*	Total formula weight	36905.3

*Water molecules are not included.