1BIM

CRYSTALLOGRAPHIC STUDIES ON THE BINDING MODES OF P2-P3 BUTANEDIAMIDE RENIN INHIBITORS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Renin	polymer	337	36939.6	2	UniProt (P00797) Pfam (PF00026)	Homo sapiens (human)	Angiotensinogenase
2	C, D (A, B)	(2S)-2-[(2-amino-1,3-thiazol-4-yl)methyl]-N~1~-{(1S,2S)-1-(cyclohexylmethyl)-2-hydroxy-2-[(3R)-1,5,5-trimethyl-2-oxopyrrolidin-3-yl]ethyl}-N~4~-[2-(dimethylamino)-2-oxoethyl]-N~4~-[(1S)-1-phenylethyl]butanediamide	non-polymer		682.9	2	Chemie (0QB)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73879.2
Non-Polymers*	Number of molecules	2
	Total formula weight	1365.8
All*	Total formula weight	75245.0

*Water molecules are not included.