1BDR
HIV-1 (2: 31, 33-37) PROTEASE COMPLEXED WITH INHIBITOR SB203386
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HIV-1 PROTEASE | polymer | 99 | 10669.6 | 2 | UniProt (P04587) Pfam (PF00077) | Human immunodeficiency virus 1 | |
| 2 | C (B) | (2R,4S,5S,1'S)-2-PHENYLMETHYL-4-HYDROXY-5-(TERT-BUTOXYCARBONYL)AMINO-6-PHENYL HEXANOYL-N-(1'-IMIDAZO-2-YL)-2'-METHYLPROPANAMIDE | non-polymer | 534.7 | 1 | Chemie (IM1) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P04587)
| PDB | External Database | Details |
|---|---|---|
| Ser 31 | Thr 99 | engineered mutation |
| Val 33 | Leu 101 | engineered mutation |
| Ala 34 | Glu 102 | conflict |
| Gly 35 | Glu 103 | engineered mutation |
| Ile 36 | Met 104 | engineered mutation |
| Glu 37 | Ser 105 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21339.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 534.7 | |
| All* | Total formula weight | 21873.9 |
