1BDQ

HIV-1 (2:31-37, 47, 82) PROTEASE COMPLEXED WITH INHIBITOR SB203386

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	HIV-1 PROTEASE	polymer	99	10683.6	2	UniProt (P04587) Pfam (PF00077) In PDB	Human immunodeficiency virus 1
2	B	(2R,4S,5S,1'S)-2-PHENYLMETHYL-4-HYDROXY-5-(TERT-BUTOXYCARBONYL)AMINO-6-PHENYL HEXANOYL-N-(1'-IMIDAZO-2-YL)-2'-METHYLPROPANAMIDE	non-polymer		534.7	1	Chemie (IM1)
3		water	water		18.0	43	Chemie (HOH)

Sequence modifications

A, B: 1 - 99 (UniProt: P04587)

PDB	External Database	Details
Ser 31	Thr 99	engineered mutation
Ile 32	Val 100	engineered mutation
Val 33	Leu 101	engineered mutation
Ala 34	Glu 102	engineered mutation
Gly 35	Glu 103	engineered mutation
Ile 36	Met 104	engineered mutation
Glu 37	Ser 105	engineered mutation
Val 47	Ile 115	engineered mutation
Ile 82	Val 150	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	21367.3
Non-Polymers*	Number of molecules	1
	Total formula weight	534.7
All*	Total formula weight	21901.9

*Water molecules are not included.