1B9T
NOVEL AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE MAKE SELECTIVE INTERACTIONS WITH CONSERVED RESIDUES AND WATER MOLECULES IN THE ACTIVE SITE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN (NEURAMINIDASE) | polymer | 390 | 43460.3 | 1 | UniProt (P03474) Pfam (PF00064) | Influenza B virus (B/Lee/40) | SIALIDASE |
| 2 | B (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 3 | C, D (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | E (A) | 1-(4-CARBOXY-2-GUANIDINOPENTYL)-5,5'-DI(HYDROXYMETHYL)PYRROLIDIN-2-ONE | non-polymer | 322.3 | 1 | Chemie (RAI) | |||
| 5 | F (A) | water | water | 18.0 | 112 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43460.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 623.7 | |
| All* | Total formula weight | 44084.0 |
