1B9F
MOBILITY OF AN HIV-1 INTEGRASE ACTIVE SITE LOOP IS CORRELATED WITH CATALYTIC ACTIVITY
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN (INTEGRASE) | polymer | 163 | 17940.5 | 1 | UniProt (P12497) Pfam (PF00665) | Human immunodeficiency virus type 1 (CLONE 12) | |
| 2 | B, C (A) | CACODYLATE ION | non-polymer | 137.0 | 2 | Chemie (CAC) | |||
| 3 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | E (A) | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
A: 50 - 212 (UniProt: P12497)
| PDB | External Database | Details |
|---|---|---|
| Ala 140 | Gly | engineered mutation |
| Ala 149 | Gly | engineered mutation |
| Lys 185 | Phe | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17940.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 370.0 | |
| All* | Total formula weight | 18310.6 |
