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1AYV

CRYSTAL STRUCTURE OF CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH A COVALENT THIAZOLHYDRAZIDE INHIBITOR

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
CATHEPSIN Kpolymer21523523.51UniProt (P43235)
Pfam (PF00112)
Homo sapiens (human)
2B
(A)
N-[2-[1-(N-BENZYLOXYCARBONYLAMINO)-3-METHYLBUTYL]THIAZOL-4-YLCARBONYL]-N'-(BENZYLOXYCARBONYL-L-LEUCINYL)HYDRAZIDEnon-polymer609.71Chemie (IN6)
3C
(A)
waterwater18.067Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight23523.5
Non-Polymers*Number of molecules1
Total formula weight609.7
All*Total formula weight24133.2
*Water molecules are not included.

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PDB entries from 2025-07-16

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