1AY6
THROMBIN INHIBITOR FROM THEONALLA, CYCLOTHEANAMIDE-BASED MACROCYCLIC TRIPEPTIDE MOTIF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | THROMBIN LIGHT CHAIN | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | |
| 2 | B (H) | THROMBIN HEAVY CHAIN | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | |
| 3 | C (I) | HIRUGEN | polymer | 13 | 1632.7 | 1 | UniProt (P01050) | Hirudo medicinalis | |
| 4 | D (H) | amino({3-[(3R,5R,14S,16S,21aR)-5,14-dihydroxy-1,4,17-trioxo-16-(2-phenylethyl)icosahydro-1H-pyrrolo[1,2-d][1,4,7,11]tetraazacyclononadecin-3-yl]propyl}amino)methaniminium | non-polymer | 588.8 | 1 | BIRD (PRD_000410) Chemie (1ZV) | |||
| 5 | E, F, G (L, H, I) | water | water | 18.0 | 176 | Chemie (HOH) |
Sequence modifications
I: 55 - 64 (UniProt: P01050)
| PDB | External Database | Details |
|---|---|---|
| Ace 52 | - | insertion |
| Asn 53 | - | insertion |
| Glu 54 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 35509.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 588.8 | |
| All* | Total formula weight | 36098.2 |
