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1AXW

E. COLI THYMIDYLATE SYNTHASE IN COMPLEX WITH METHOTREXATE (MTX) AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BTHYMIDYLATE SYNTHASEpolymer26530543.72UniProt (P0A884)
Pfam (PF00303)
In PDB
Escherichia coliTS, THYMIDYLATE SYNTHETASE
2A, B2'-DEOXYURIDINE 5'-MONOPHOSPHATEnon-polymer308.22Chemie (UMP)
3A, BMETHOTREXATEnon-polymer454.42Chemie (MTX)
4waterwater18.0188Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight61087.3
Non-Polymers*Number of molecules4
Total formula weight1525.2
All*Total formula weight62612.6
*Water molecules are not included.

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