1AXW
E. COLI THYMIDYLATE SYNTHASE IN COMPLEX WITH METHOTREXATE (MTX) AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | THYMIDYLATE SYNTHASE | polymer | 265 | 30543.7 | 2 | UniProt (P0A884) Pfam (PF00303) | Escherichia coli | TS, THYMIDYLATE SYNTHETASE |
| 2 | C, E (A, B) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 2 | Chemie (UMP) | |||
| 3 | D, F (A, B) | METHOTREXATE | non-polymer | 454.4 | 2 | Chemie (MTX) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 188 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61087.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1525.2 | |
| All* | Total formula weight | 62612.6 |
