1AXW

E. COLI THYMIDYLATE SYNTHASE IN COMPLEX WITH METHOTREXATE (MTX) AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	THYMIDYLATE SYNTHASE	polymer	265	30543.7	2	UniProt (P0A884) Pfam (PF00303)	Escherichia coli	TS, THYMIDYLATE SYNTHETASE
2	C, E (A, B)	2'-DEOXYURIDINE 5'-MONOPHOSPHATE	non-polymer		308.2	2	Chemie (UMP) PubChem (688) PubChem (65063) PubChem (446899) PubChem (446900) PubChem (57164254) PubChem (71773959) PubChem (92144438) PubChem (92209480) PubChem (92209481) PubChem (92209482) PubChem (92449733) PubChem (133126534)
3	D, F (A, B)	METHOTREXATE	non-polymer		454.4	2	Chemie (MTX) PubChem (4112) PubChem (72440) PubChem (126941)
4	G, H (A, B)	water	water		18.0	188	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	61087.3
Non-Polymers*	Number of molecules	4
	Total formula weight	1525.2
All*	Total formula weight	62612.6

*Water molecules are not included.