1AXA
ACTIVE-SITE MOBILITY IN HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE AS DEMONSTRATED BY CRYSTAL STRUCTURE OF A28S MUTANT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HIV-1 PROTEASE | polymer | 99 | 10819.8 | 2 | UniProt (P03366) Pfam (PF00077) | Human immunodeficiency virus 1 | |
| 2 | C, D (A) | N-[[1-[N-ACETAMIDYL]-[1-CYCLOHEXYLMETHYL-2-HYDROXY-4-ISOPROPYL]-BUT-4-YL]-CARBONYL]-GLUTAMINYL-ARGINYL-AMIDE | non-polymer | 596.8 | 2 | Chemie (U0E) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P03366)
| PDB | External Database | Details |
|---|---|---|
| Ser 28 | Ala 96 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21639.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1193.5 | |
| All* | Total formula weight | 22833.0 |
