1AKA
STRUCTURAL BASIS FOR THE CATALYTIC ACTIVITY OF ASPARTATE AMINOTRANSFERASE K258H LACKING ITS PYRIDOXAL-5'-PHOSPHATE-BINDING LYSINE RESIDUE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ASPARTATE AMINOTRANSFERASE | polymer | 401 | 45001.5 | 2 | UniProt (P00508) Pfam (PF00155) | Gallus gallus (chicken) | |
| 2 | C (A) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
| 3 | D (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 666 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 410 (UniProt: P00508)
| PDB | External Database | Details |
|---|---|---|
| Pro 47 | Ser 67 | conflict |
| His 258 | Lys 272 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90002.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 342.1 | |
| All* | Total formula weight | 90345.0 |
