1AHW
A COMPLEX OF EXTRACELLULAR DOMAIN OF TISSUE FACTOR WITH AN INHIBITORY FAB (5G9)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | IMMUNOGLOBULIN FAB 5G9 (LIGHT CHAIN) | polymer | 214 | 23810.2 | 2 | UniProt (P01837) Pfam (PF07654) | Mus musculus (house mouse) | FAB, FAB LIGHT CHAIN, FAB HEAVY CHAIN |
| 2 | B, E (B, E) | IMMUNOGLOBULIN FAB 5G9 (HEAVY CHAIN) | polymer | 214 | 23175.8 | 2 | PIR (S49220) Pfam (PF07654) UniProt (by SIFTS) (P01868) | Mus musculus (house mouse) | FAB, FAB LIGHT CHAIN, FAB HEAVY CHAIN |
| 3 | C, F (C, F) | TISSUE FACTOR | polymer | 219 | 24826.5 | 2 | UniProt (P13726) Pfam (PF01108) Pfam (PF09294) | Homo sapiens (human) | TF, THROMBOPLASTIN, COAGULATION FACTOR III |
Sequence modifications
A, D: 1 - 214 (UniProt: P01837)
B, E: 3 - 214 (PIR: S49220)
| PDB | External Database | Details |
|---|---|---|
| Arg 30 | Tyr 30 | conflict |
| Lys 31 | Ser 31 | conflict |
| Asn 34 | Ser 34 | conflict |
| Tyr 36 | Phe 36 | conflict |
| Trp 41 | Gly 41 | conflict |
| Tyr 50 | Arg 50 | conflict |
| Thr 52 | Asn 52 | conflict |
| Ser 53 | Arg 53 | conflict |
| Ala 55 | Val 55 | conflict |
| Ser 80 | Tyr 80 | conflict |
| Asp 81 | Glu 81 | conflict |
| Thr 83 | Leu 83 | conflict |
| Ala 84 | Gly 84 | conflict |
| Thr 85 | Ile 85 | conflict |
| His 91 | Phe 91 | conflict |
| Gly 92 | Asp 92 | conflict |
| Ser 94 | Phe 94 | conflict |
| Asn 107 | Lys 107 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Glu 1 | - | insertion |
| Ile 2 | - | insertion |
| - | Val 2 | deletion |
| - | Lys 3 | deletion |
| Gln 5 | Leu 5 | conflict |
| Gln 6 | Glu 6 | conflict |
| Arg 13 | Lys 13 | conflict |
| Pro 14 | Ser 14 | conflict |
| Leu 17 | Ser 17 | conflict |
| Lys 23 | Thr 23 | conflict |
| Tyr 32 | Thr 32 | conflict |
| Leu 50 | Arg 50 | conflict |
| Glu 54 | Ala 54 | conflict |
| Asn 57 | Glu 57 | conflict |
| Thr 58 | Ile 58 | conflict |
| Ile 59 | Lys 59 | conflict |
| Lys 67 | Thr 67 | conflict |
| Ser 69 | Thr 69 | conflict |
| Ser 76 | Thr 76 | conflict |
| Ala 97 | Val 97 | conflict |
| - | Arg 99 | deletion |
| - | Gly 100 | deletion |
| Asp 99 | Tyr 101 | conflict |
| Asn 100 | Gly 102 | conflict |
| Tyr 102 | Ser 104 | conflict |
| Tyr 103 | Gln 105 | conflict |
| Phe 104 | Glu 106 | conflict |
| Asp 105 | Pro 107 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 143625.0 | |
| All* | Total formula weight | 143625.0 |
