1AGM
Refined structure for the complex of acarbose with glucoamylase from Aspergillus awamori var. x100 to 2.4 angstroms resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GLUCOAMYLASE-471 | polymer | 470 | 50450.7 | 1 | UniProt (P23176) Pfam (PF00723) UniProt (by SIFTS) (P69327) | Aspergillus awamori | |
| 2 | B (B) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G42227JK) | |||
| 3 | C (C) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1397.2 | 1 | In PDB GlyTouCan (G83582BK) | |||
| 4 | D, E (D, E) | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 645.6 | 2 | In PDB BIRD (PRD_900007) GlyTouCan (G66431MI) | alpha-acarbose | ||
| 5 | F, G, H, I, J... (A) | alpha-D-mannopyranose | non-polymer | 180.2 | 10 | Chemie (MAN) | |||
| 6 | P (A) | water | water | 18.0 | 535 | Chemie (HOH) |
Sequence modifications
A: 1 - 471 (UniProt: P23176)
| PDB | External Database | Details |
|---|---|---|
| Leu 58 | Ile 82 | conflict |
| Ile 60 | Leu 84 | conflict |
| Thr 117 | Ala 140 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 50450.7 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 3599.3 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1801.6 | |
| All* | Total formula weight | 55851.6 |
