1A7Q

FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) HIGH AFFINITY EXPRESSED VARIANT CONTAINING SER26L->GLY, ILE29L->THR, GLU81L->ASP, THR97L->SER, PRO240H->LEU, ASP258H->ALA, LYS281H->GLU, ASN283H->ASP AND LEU312H->VAL

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (L)	IGG1-KAPPA D1.3 FV (LIGHT CHAIN)	polymer	106	11457.7	1	GenBank (545862) Pfam (PF07686) UniProt (by SIFTS) (P01635)	Mus musculus (house mouse)
2	B (H)	IGG1-KAPPA D1.3 FV (HEAVY CHAIN)	polymer	116	12816.2	1	GenBank (896294) Pfam (PF07686) UniProt (by SIFTS) (P01820)	Mus musculus (house mouse)
3	C, D (L, H)	water	water		18.0	47	Chemie (HOH)

Sequence modifications

L: 1 - 106 (GenBank: 545862)

PDB	External Database	Details
Val 3	Glu 3	conflict
Gly 26	Ser 26	variant
Thr 29	Ile 29	variant
Tyr 50	Lys 50	conflict
Thr 51	Ala 51	conflict
Thr 52	Gln 52	conflict
Ala 56	Asp 56	conflict
Asp 81	Glu 81	variant
-	Pro 95	deletion
Arg 96	Trp 97	conflict
Ser 97	Thr 98	variant

H: 201 - 316 (GenBank: 896294)

PDB	External Database	Details
Leu 240	Pro 172	variant
Ala 258	Asp 190	variant
Glu 281	Lys 213	variant
Asp 283	Asn 215	variant

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	24273.9
All*	Total formula weight	24273.9

*Water molecules are not included.