1A7A

STRUCTURE OF HUMAN PLACENTAL S-ADENOSYLHOMOCYSTEINE HYDROLASE: DETERMINATION OF A 30 SELENIUM ATOM SUBSTRUCTURE FROM DATA AT A SINGLE WAVELENGTH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	S-ADENOSYLHOMOCYSTEINE HYDROLASE	polymer	432	48522.3	2	UniProt (P23526) Pfam (PF05221) Pfam (PF00670)	Homo sapiens (human)
2	C, E (A, B)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3	D, F (A, B)	(1'R,2'S)-9-(2-HYDROXY-3'-KETO-CYCLOPENTEN-1-YL)ADENINE	non-polymer		233.2	2	Chemie (ADC)
4	G, H (A, B)	water	water		18.0	46	Chemie (HOH)

Sequence modifications

A, B: 2 - 432 (UniProt: P23526)

PDB	External Database	Details
Mse 29	Met 29	engineered mutation
Mse 33	Met 33	engineered mutation
Mse 35	Met 35	engineered mutation
Mse 56	Met 56	engineered mutation
Mse 127	Met 127	engineered mutation
Mse 167	Met 167	engineered mutation
Mse 168	Met 168	engineered mutation
Mse 210	Met 210	engineered mutation
Mse 254	Met 254	engineered mutation
Mse 262	Met 262	engineered mutation
Mse 290	Met 290	engineered mutation
Mse 351	Met 351	engineered mutation
Mse 358	Met 358	engineered mutation
Mse 367	Met 367	engineered mutation
Mse 419	Met 419	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	97044.6
Non-Polymers*	Number of molecules	4
	Total formula weight	1793.3
All*	Total formula weight	98837.9

*Water molecules are not included.