1A36
TOPOISOMERASE I/DNA COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | DNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*A P*TP*TP*TP*TP*T)- 3') | polymer | 22 | 6790.5 | 1 | |||
| 2 | B (C) | DNA (5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*C P*TP*TP*TP*TP*T)- 3') | polymer | 22 | 6705.4 | 1 | |||
| 3 | C (A) | TOPOISOMERASE I | polymer | 591 | 70022.9 | 1 | UniProt (P11387) Pfam (PF02919) Pfam (PF01028) Pfam (PF14370) | Homo sapiens (human) | |
| 4 | D, E, F (B, C, A) | water | water | 18.0 | 57 | Chemie (HOH) |
Sequence modifications
A: 175 - 765 (UniProt: P11387)
| PDB | External Database | Details |
|---|---|---|
| Phe 723 | Tyr 723 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 83518.7 | |
| All* | Total formula weight | 83518.7 |
