1ZLA
X-ray Structure of a Kaposi's sarcoma herpesvirus LANA peptide bound to the nucleosomal core
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (I, J) | Palindromic 146bp Human alpha-Satellite DNA fragment | polymer | 146 | 45054.8 | 2 | Homo sapiens (human) | ||
| 2 | C, G (A, E) | histone H3 | polymer | 135 | 15341.0 | 2 | GenBank (288992) Pfam (PF00125) UniProt (by SIFTS) (P84233) | Xenopus laevis (African clawed frog) | |
| 3 | D, H (B, F) | Histone H4 | polymer | 102 | 11263.2 | 2 | UniProt (P62799) Pfam (PF15511) | Xenopus laevis (African clawed frog) | |
| 4 | E, I (C, G) | Xenopus laevis-like histone H2A | polymer | 129 | 14181.4 | 2 | GenBank (30268540) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P06897) | Expression vector pET3-H2A | |
| 5 | F, J (D, H) | histone H2B | polymer | 125 | 13794.0 | 2 | GenBank (296216) Pfam (PF00125) UniProt (by SIFTS) (P02281) | Xenopus laevis (African clawed frog) | |
| 6 | K (K) | latent nuclear antigen | polymer | 22 | 2260.6 | 1 | GenBank (5669894) UniProt (by SIFTS) (Q9DUM3) | ||
| 7 | L, M, N, O, P... (I, J, A, B, C...) | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A, E: 401 - 535 (GenBank: 288992)
C, G: 801 - 929 (GenBank: 30268540)
| PDB | External Database | Details |
|---|---|---|
| Ala 511 | Gly 112 | engineered mutation |
| His 518 | Thr 119 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Trp 869 | Ala 70 | engineered mutation |
| Glu 870 | Ala 71 | engineered mutation |
| Thr 926 | Ala 127 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 201529.6 | |
| All* | Total formula weight | 201529.6 |
