1X9N
Crystal Structure of Human DNA Ligase I bound to 5'-adenylated, nicked DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | dideoxy terminated DNA | polymer | 13 | 3982.6 | 1 | |||
| 2 | B (C) | 5'-phosphorylated DNA | polymer | 15 | 4641.0 | 1 | |||
| 3 | C (D) | template DNA | polymer | 28 | 8529.5 | 1 | |||
| 4 | D (A) | DNA ligase I | polymer | 688 | 76609.3 | 1 | UniProt (P18858) Pfam (PF04675) Pfam (PF01068) Pfam (PF04679) | Homo sapiens (human) | Polydeoxyribonucleotide synthase [ATP] |
| 5 | E (C) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (34768) PubChem (83862) PubChem (40467049) PubChem (40469468) PubChem (446048) PubChem (44348067) PubChem (45358029) PubChem (40459109) PubChem (515384) PubChem (46874558) PubChem (638042) PubChem (46875232) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (5316444) PubChem (5742864) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (12163610) PubChem (12358355) PubChem (92144436) PubChem (122197642) PubChem (12358354) PubChem (162290139) PubChem (162946266) PubChem (171699505) |
Sequence modifications
A: 233 - 919 (UniProt: P18858)
| PDB | External Database | Details |
|---|---|---|
| Met 232 | - | initiating methionine |
| Mse 308 | Met 308 | modified residue |
| Mse 393 | Met 393 | modified residue |
| Mse 480 | Met 480 | modified residue |
| Mse 501 | Met 501 | modified residue |
| Mse 543 | Met 543 | modified residue |
| Mse 723 | Met 723 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 93762.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 347.2 | |
| All* | Total formula weight | 94109.6 |
