13LZ
Crystal Structure of Human Inositol 1,3,4-Trisphosphate 5/6-kinase (ITPK1) in Complex with an Inhibitor NCGC00879727
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Inositol-tetrakisphosphate 1-kinase | polymer | 331 | 37304.4 | 2 | UniProt (Q13572) Pfam (PF17927) Pfam (PF05770) | Homo sapiens (human) | Inositol 1,3,4-trisphosphate 5/6-kinase,Inositol-triphosphate 5/6-kinase,Ins(1,4)P(3) 5/6-kinase |
| 2 | C, F (A, B) | N-ethyl[1]benzofuro[3,2-d]pyrimidin-4-amine | non-polymer | 213.2 | 2 | Chemie (A1DHL) | |||
| 3 | D, E, G, H, I... (A, B) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 4 | L, M (A, B) | water | water | 18.0 | 160 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 327 (UniProt: Q13572)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 74608.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1098.9 | |
| All* | Total formula weight | 75707.8 |
