13LQ
Structure of human TRPV3-G568D Olmsted syndrome mutant in the 4-fold symmetrical open state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Isoform 2 of Transient receptor potential cation channel subfamily V member 3,Green fluorescent protein | polymer | 1052 | 120196.0 | 4 | UniProt (Q8NET8) UniProt (P42212) | Homo sapiens (human) | |
| 2 | E, F, G (A) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) PubChem (923) |
Sequence modifications
A, B, C, D: 1 - 791 (UniProt: Q8NET8)
A, B, C, D: 803 - 1039 (UniProt: P42212)
| PDB | External Database | Details |
|---|---|---|
| Asp 568 | Gly 568 | engineered mutation |
| Leu 792 | - | linker |
| Val 793 | - | linker |
| Pro 794 | - | linker |
| Arg 795 | - | linker |
| Gly 796 | - | linker |
| Ser 797 | - | linker |
| Ala 798 | - | linker |
| Ala 799 | - | linker |
| Ala 800 | - | linker |
| Ala 801 | - | linker |
| Val 802 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Leu 865 | Phe 64 | conflict |
| Thr 866 | Ser 65 | conflict |
| Lys 1007 | Ala 206 | conflict |
| Leu 1032 | His 231 | conflict |
| Ser 1040 | - | expression tag |
| Gly 1041 | - | expression tag |
| Leu 1042 | - | expression tag |
| Arg 1043 | - | expression tag |
| Ser 1044 | - | expression tag |
| Trp 1045 | - | expression tag |
| Ser 1046 | - | expression tag |
| His 1047 | - | expression tag |
| Pro 1048 | - | expression tag |
| Gln 1049 | - | expression tag |
| Phe 1050 | - | expression tag |
| Glu 1051 | - | expression tag |
| Lys 1052 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 480784.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 69.0 | |
| All* | Total formula weight | 480852.9 |
