13FW

273 K Structure of Human Spermidine Synthase in Complex with 5-deoxy-5-methylthioadenosine and Putrescine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Spermidine synthase	polymer	315	35538.4	2	UniProt (P19623) Pfam (PF17284) Pfam (PF01564)	Homo sapiens (human)	SPDSY,Putrescine aminopropyltransferase
2	C, E (A, B)	5'-DEOXY-5'-METHYLTHIOADENOSINE	non-polymer		297.3	2	Chemie (MTA) PubChem (439176)
3	D, F (A, B)	1,4-DIAMINOBUTANE	non-polymer		88.2	2	Chemie (PUT) PubChem (1045)
4	G, H (A, B)	water	water		18.0	410	Chemie (HOH)

Sequence modifications

A, B: 2 - 302 (UniProt: P19623)

PDB	External Database	Details
Met -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
Glu -5	-	expression tag
Asn -4	-	expression tag
Leu -3	-	expression tag
Tyr -2	-	expression tag
Phe -1	-	expression tag
Gln 0	-	expression tag
Gly 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71076.8
Non-Polymers*	Number of molecules	4
	Total formula weight	771.0
All*	Total formula weight	71847.8

*Water molecules are not included.