13FL

Structure of FabS1CE2_P2a in complex with the N-terminal domain of PD-L1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	FabS1CE2_P2a heavy chain	polymer	227	24385.4	1		Homo sapiens (human)
2	B (B)	FabS1CE2_P2a light chain (Trastuzumab Fab Light Chain)	polymer	212	23225.7	1		Homo sapiens (human)
3	C (C)	Programmed cell death 1 ligand 1	polymer	126	14502.6	1	UniProt (Q9NZQ7) Pfam (PF07686)	Homo sapiens (human)	PD-L1,PDCD1 ligand 1,Programmed death ligand 1,hPD-L1,B7 homolog 1,B7-H1
4	D (A)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
5	E, F, H (A, B, C)	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL) PubChem (312)
6	G (C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG) PubChem (24139)
7	I, J, K (A, B, C)	water	water		18.0	94	Chemie (HOH)

Sequence modifications

C: 19 - 132 (UniProt: Q9NZQ7)

PDB	External Database	Details
Leu 133	-	expression tag
Val 134	-	expression tag
Pro 135	-	expression tag
Arg 136	-	expression tag
Gly 137	-	expression tag
Ser 138	-	expression tag
His 139	-	expression tag
His 140	-	expression tag
His 141	-	expression tag
His 142	-	expression tag
His 143	-	expression tag
His 144	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	62113.7
Non-Polymers*	Number of molecules	5
	Total formula weight	389.6
All*	Total formula weight	62503.3

*Water molecules are not included.