13CV
Crystal structure of covalent inhibitor 3-(2-chloroacetamido)-N-(pyridin-2-yl)benzamide bound to Ubiquitin C-terminal Hydrolase-L3
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Ubiquitin carboxyl-terminal hydrolase isozyme L3 | polymer | 235 | 26625.0 | 4 | UniProt (P15374) | Homo sapiens (human) | UCH-L3,Ubiquitin thioesterase L3 |
| 2 | E, J, M, O (A, B, C, D) | 3-(2-chloroacetamido)-N-(pyridin-2-yl)benzamide | non-polymer | 289.7 | 4 | Chemie (A1DFD) | |||
| 3 | F, G, H, I, K... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 4 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 305 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 230 (UniProt: P15374)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 106500.1 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2119.5 | |
| All* | Total formula weight | 108619.6 |
