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12YZ

Crystal structure of human K293st geranylgeranyl diphosphate synthase with 5 geranylgeranyl diphosphate bound and 1 magnesium only subunits

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Geranylgeranyl pyrophosphate synthasepolymer29434093.96UniProt (O95749)
Pfam (PF00348)
Homo sapiens (human)GGPP synthase,GGPPSase,(2E,6E)-farnesyl diphosphate synthase,Dimethylallyltranstransferase,Farnesyl diphosphate synthase,Farnesyltranstransferase,Geranylgeranyl diphosphate synthase,Geranyltranstransferase
2G, H, J, K, L...
(A, B, C, D, E...)
MAGNESIUM IONnon-polymer24.312Chemie (MG)
PubChem (888)
3I, N, Q, T, W
(A, C, D, E, F)
GERANYLGERANYL DIPHOSPHATEnon-polymer450.45Chemie (GRG)
4AA, BA, CA, X, Y...
(D, E, F, A, B...)
waterwater18.02143Chemie (HOH)
Sequence modifications
A, B, C, D, E, F: 1 - 293 (UniProt: O95749)
PDBExternal DatabaseDetails
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight204563.5
Non-Polymers*Number of molecules17
Total formula weight2543.9
All*Total formula weight207107.4
*Water molecules are not included.

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PDB entries from 2026-11-04

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