12KX
Crystal structure of H5 hemagglutinin D190/H226 from the A/British_Columbia/PHL-2032/2024 (H5N1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (I, A, C) | Hemagglutinin HA1 | polymer | 323 | 36328.2 | 3 | UniProt (A0A2R4A6J1) | Influenza A virus | |
| 2 | B, D, F (J, B, D) | Hemagglutinin HA2 | polymer | 174 | 20114.2 | 3 | UniProt (A0A8E4IDS0) | Influenza A virus | |
| 3 | G (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | H, I, J, K, L... (I, A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) PubChem (24139) |
Sequence modifications
I, A, C: 11 - 324 (UniProt: A0A2R4A6J1)
| PDB | External Database | Details |
|---|---|---|
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| Ala 46 | Thr 52 | conflict |
| Asp 190 | Glu 202 | engineered mutation |
| His 226 | Gln 238 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 169327.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1548.5 | |
| All* | Total formula weight | 171300.0 |
