12CV
Crystal Structure of human JNK1 Kinase Domain in complex with inhibitor CCD-2728
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 8 | polymer | 358 | 41375.9 | 1 | UniProt (P45983) Pfam (PF00069) | Homo sapiens (human) | MAP kinase 8,MAPK 8,JNK-46,Stress-activated protein kinase 1c,SAPK1c,Stress-activated protein kinase JNK1,c-Jun N-terminal kinase 1 |
| 2 | B (A) | (4M)-N-[3-(dimethylcarbamoyl)-4-hydroxyphenyl]-4-(1H-pyrrolo[2,3-b]pyridin-5-yl)-3H-1lambda~4~-benzothiophene-2-carboxamide | non-polymer | 458.5 | 1 | Chemie (A1DBX) | |||
| 3 | C (A) | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41375.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 458.5 | |
| All* | Total formula weight | 41834.4 |
